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Research Laoratories
Affiliated Groups
EDUCATION

Mission of the Global Health Institute

The Global Health Institute (GHI) has been created to contribute to the understanding, diagnosis, prevention and treatment of infectious diseases, which still claim 18 million lives each year and account for half of the deaths in the developing world. The GHI is currently composed of 8 groups, whose activities already reflect the Institute's future ambitions. Basic mechanisms of host-pathogen interactions and innate immunity towards pathogens are being studied using multidisciplinary approaches. Crucial world health issues, like tuberculosis and HIV/AIDS, are being tackled. These include understanding, and hopefully counteracting, the persistence of Mycobacterium tuberculosis, the causative agent of tuberculosis, or designing drugs to treat this disease. Mechanisms of HIV infection and use of this virus in gene therapy approaches are also the subject of intense research. Further recruitment is planned, in particular of talented young researchers, to extend these efforts to other pathogenic bacteria and viruses. Intensification of current research themes by including novel technological approaches is also a priority.

SAVE THE DATE !!!

 
 
 
 
Wednesday, March 17th, 2010 @ 15.30
Inauguration of our new P3 Laboratory
More information here

Web News


14.01.2010 : Biologists wake dormant viruses and uncover mechanism for survival. It is known that viral "squatters" comprise nearly half of our genetic code. These genomic invaders inserted their DNA into our own millions of years ago when they infected our ancestors. But just how we keep them quiet and prevent them from attack was more of a mystery until EPFL researchers revived them. The reason we survive the presence of these endogenous retroviruses-viruses that attack and are passed on through germ cells, the cells that give rise to eggs and sperm-is because something keeps the killers silent. Now, publishing in the journal Nature, Didier Trono and his team from EPFL, in Switzerland, describe the mechanism. Their results provide insights into evolution and suggest potential new therapies in fighting another retrovirus-HIV ...more


8.12.2009 : Congratulations to Prof. Stewart Cole and his team who have been awarded the Kochon Prize, foreseen for persons, institutions, or organizations that have made a highly significant contribution to combating tuberculosis; Professor Stewart Cole will share this prize with Ms Lucy Chesire, a leading international patient activist who has achieved important TB advancements at both global and regional levels, on the 5th of December this year. They will share the prize that consists of a medal and US$ 65,000...more
The selections were announced at the opening ceremony of the World Conference of the International Union Against Tuberculosis and Lung Disease, held in Cancun, Mexico. More...


25.11.2009 :  We are glad to announce the creation of a joint research unit INSERM-EPFL. This new unit is located within the Global Health Institute and is directed by Prof. Christian Doerig. The group studies the role of protein phosphorylation in the control of cell proliferation and differentiation in Plasmodium falciparum, the parasitic protist responsible for the most virulent form of human malaria; one of the objectives is to identify protein kinase inhibitors that can represent leads for the development of novel antimalarials.   The laboratory has made important contributions to the fields of signal transduction, cell cycle control and kinomics in malaria parasites The team...


02.11.2009 : Leprosy still affects hundreds of thousands of people today throughout the entire world. An international team headed by EPFL professor Stewart Cole has traced the history of the disease from ancient Egypt to today and in doing so has made a public health study essential for combating the disease...more


Research fields

Laboratory of Prof. Melanie Blokesch
Laboratory of Molecular Microbiology

Laboratory of Prof. Stewart Cole
Drug discovery for the treatment of tuberculosis as well as phylogeography and immunodiagnosis of leprosy

Joint research unit INSERM-EPFL, headed by Prof. Christian Doerig
Role of protein phosphorylation in the control of cell proliferation and differentiation in Plasmodium falciparum

Laboratory of Prof. Nicola Harris
Laboratory of Intestinal Immunology

Laboratory of Prof. Bruno Lemaitre
Mechanisms of microbial infection and corresponding host defense responses in Drosophila

Laboratory of Prof. John McKinney
Persistence mechanisms in Mycobacterium tuberculosis

Laboratory of Prof. Didier Trono
Retroelements as essential constituents of the human genome, potential lethal invaders and powerful research tool

Laboratory of Prof. Gisou van der Goot
Molecular understanding of the interaction between bacterial toxins and he mammalian host cells

Contact
Head of the Institute

Prof. Stewart Cole

Office : SV 3531


Administration

Caroline Guinchard

Office : AI 3151


Address

EPFL-SV-GHI

Station 19

CH-1015 Lausanne

Ph:+41 (0)21 693 17 94

Fx:+41 (0)21 693 95 38

 

General information :

please email us


Location
NEW
PRESENTATION
Presentation of the Global Health Institute
Leaflet [pdf]
 

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